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David John Nutt born 16 April is an English neuropsychopharmacologist specialising in the research of drugs that affect the brain and conditions such as addiction , anxiety , and sleep. Nutt completed his secondary education at Bristol Grammar School and then studied medicine at Downing College, Cambridge , graduating in In , he completed his clinical training at Guy's Hospital. This work culminated in a ground-breaking paper in Nature journal in  which described the concept of inverse agonism using his preferred term, "contragonism" for the first time. From to , he lectured in psychiatry at the University of Oxford. In Nutt published a controversial study on the harms of drug use in The Lancet. This ranked the harm done to user and society by a range of drugs.